Lipophilic Micronutrients and Adipose Tissue Biology
نویسندگان
چکیده
منابع مشابه
Lipophilic Micronutrients and Adipose Tissue Biology
Lipophilic micronutrients (LM) constitute a large family of molecules including several vitamins (A, D, E, K) and carotenoids. Their ability to regulate gene expression is becoming increasingly clear and constitutes an important part of nutrigenomics. Interestingly, adipose tissue is not only a main storage site for these molecules within the body, but it is also subjected to the regulatory eff...
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BROWN ADIPOSE TISSUE Brown adipose tissue (BAT) (Figure 1) has been recognized as a key thermogenic tissue in rodents for several decades. However, in the last few years, there has been a resurgent interest in the biology and therapeutic potential of BAT. This has been largely driven by a new understanding that most, if not all, healthy adult humans have significant deposits of BAT which can be...
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It is epidemiologically established that obesity is frequently associated with the metabolic syndrome and poses an increased risk for the development of type 2 diabetes mellitus and cardiovascular disease. The molecular links that connect the phenomenon of obesity, per se, with insulin resistance and cardiovascular disease are still not fully elucidated. It is increasingly apparent that fully f...
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In recent years, the importance of vitamin A in adipose tissue biology, obesity and type II diabetes has become apparent. This review focuses on recent developments within the area of vitamin A and adipose tissue biology. Adipose tissue has an active vitamin A metabolism as it not only stores vitamin A but retinol is also converted to its active metabolite retinoic acid. Several mouse models po...
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Interest in the biology of brown adipose tissue (BAT) has moved from the field of cold adaptation and cellular bioenergetics to the field of nutrition and obesity in recent years. This is mainly due to studies on BAT of ‘cafeteria-fed’ or obese rodents (Rothwell & Stock, 1979; Himms-Hagen, 1985; Trayhurn, 1986). In fact most studies on BAT have been focused on direct or indirect assay of the un...
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ژورنال
عنوان ژورنال: Nutrients
سال: 2012
ISSN: 2072-6643
DOI: 10.3390/nu4111622